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Adult Polycystic Kidney Disease DNA detection |
| Test | Adult Polycystic Kidney Disease DNA detection |
| Indication | This test can detect DNA linkage association with major genetic mutation. The test can indicate can help in early detection in a family with history of autosomal dominant polycstic disease. Test is required for prenatal diagnosis in couples known to be carriers of the recessive form of polycystic kidney disease. |
| Physiology | Autosomal dominant polycystic kidney disease is common fatal inherited disorder which approximately 1 in 1000 people. Polycystic kidney disease is characterised by progressive increase and enlargement of numerous fluid filled renal cysts. Cysts are present in spleen, liver, pancreas, spleen, subarachnoid space and pineal gland. |
| Sample | Laboratory generally provides an interpretive report. |
| Test Method | Southern blotting technique. |
| Related Tests | Blood, amniotic fluid, chorionic villus, tissue |
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